Switchable molecular tweezers: design and applications

• Pablo Msellem,
• Maksym Dekthiarenko,
• Nihal Hadj Seyd and
• Guillaume Vives

Beilstein J. Org. Chem. 2024, 20, 504–539, doi:10.3762/bjoc.20.45

• macroscopic analogs, exhibit mechanical motion between an open and closed conformation in response to stimuli. Such systems constitute an essential component of artificial molecular machines. This review will present selected examples of switchable molecular tweezers and their potential applications. The

• , and molecular machines. In particular, the advent of artificial molecular machines [13][14], consisting of an assembly of molecular components that perform mechanical-like motions in response to specific stimuli, has inspired the development of stimuli-responsive molecular tweezers, which have

Tetrathiafulvalene – a redox-switchable building block to control motion in mechanically interlocked molecules

• Hendrik V. Schröder and
• Christoph A. Schalley

Beilstein J. Org. Chem. 2018, 14, 2163–2185, doi:10.3762/bjoc.14.190

• Hendrik V. Schroder Christoph A. Schalley Institut für Chemie und Biochemie, Organische Chemie, Freie Universität Berlin, Takustraße 3, 14195 Berlin, Germany 10.3762/bjoc.14.190 Abstract With the rise of artificial molecular machines, control of motion on the nanoscale has become a major

• MIMs and their applications. A brief historical overview and a selection of important examples from the past until now are given. Furthermore, we will highlight our latest research on TTF-based rotaxanes. Keywords: artificial molecular machines; mechanically interlocked molecules; molecular switches

• gradients control repetitive motions of these biological nanomachines, researchers have been seeking for synthetic analogues, i.e., artificial molecular machines (AMMs), with the ultimate goal to convert energy into directional mechanical motion on the nanoscale [4][5][6]. The field of AMMs beautifully

The importance of the rotor in hydrazone-based molecular switches

• Xin Su,
• Timo Lessing and
• Ivan Aprahamian

Beilstein J. Org. Chem. 2012, 8, 872–876, doi:10.3762/bjoc.8.98

• isomerization; hydrazone; molecular switches; pH activation; structure–property analysis; Findings Nature is full of elegant examples of perfectly designed biological motors and machines [1] that perform delicate and precise tasks. Primitive as they may be, numerous artificial molecular machines [2][3][4][5][6